Publications

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The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands. Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P. Cell Rep 19 1394-1405 (2017). DOI: 10.1016/j.celrep.2017.04.059

Structural interplay between adaptive and germline recognition determines the functional bandwidth of TCR/peptide-MHC cross-reactivity. Adams JJ*, Narayanan S*, Birnbaum ME*, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Nature Immunology 17 87-94 (2016). DOI: 10.1038/ni.3310

Control of synaptic connectivity by a network of Drosophila IgSF cell surface proteins. Carrillo RA, Ozkan E, Menon KP, Nagarkar-Jaiswal S, Lee PT, Jeon M, Birnbaum ME, Bellen HJ, Garcia KC, Zinn K. Cell 163 1770-82 (2015). DOI: 10.1016/j.cell.2015.11.022

Filamentous Bacteriophage Promote Biofilm Assembly and Function. Secor PR, Sweere JM, Michaels LA, Malkovskiy AV, Lazzareschi D, Katznelson E, Rajadas J, Birnbaum ME, Arrigoni A, Braun KR, Evanko SP, Stevens DA, Kaminsky W, Singh PK, Parks WC, Bollyky PL. Cell Host Microbe 18 549-559 (2015). DOI: 10.1016/j.chom.2015.10.013

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes. Yu W, Jiang N, Ebert PJR, Kidd BA, Muller S, Lund PJ, Juang J, Adachi K, Tse T, Birnbaum ME, Newell EW, Grotenbreg GM, Valitutti S, Quake SR, Davis MM. Immunity 42 929-941 (2015). DOI: 10.1016/j.immuni.2015.05.001

Self-determination in the T cell repertoire. Birnbaum ME and Garcia KC. Immunity 42 8-10 (2015). DOI: 10.1016/j.immuni.2014.12.025

Molecular architecture of the αβTCR-CD3 complex. Birnbaum ME*, Berry R*, Hsiao YS*, Chen Z, Shingu-Vasquez MA, Yu X, Waghray D, Fischer S, McCluskey J, Rossjohn J, Walz T, Garcia KC. Proc Natl Acad Sci USA. 111 17576-81 (2014). DOI: 10.1073/pnas.1420936111

Deconstructing the peptide-MHC specificity of T cell recognition. Birnbaum ME, Mendoza JL, Sethi DK, Dong S, Glanville J, Dobbins J, Ozkan E, Davis MM, Wucherpfennig KW, Garcia KC. Cell 157 1073-1087 (2014). DOI: 10.1016/j.cell.2014.03.047

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model. Kim T, Vidal GS, Djurisic M, William CM, Birnbaum ME, Garcia KC, Hyman BT, Shatz CJ. Science 341 1399-1404 (2013). DOI: 10.1126/science.1242077

Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function. Birnbaum ME, Dong S, Garcia KC. Immunol Rev 250 82-101 (2012). DOI: 10.1111/imr.12006

A closer look at TCR germline recognition. Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. Immunity 36 887-888 (2012). DOI: 10.1016/j.immuni.2012.05.018

T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Adams JJ, Narayanan S, Liu B, Birnbaum ME, Kruse AC, Bowerman NA, Chen W, Levin AM, Connolly M, Zhu C, Kranz DM, Garcia KC. Immunity 35 681-693 (2011). DOI: 10.1016/j.immuni.2011.09.013

Molecular basis for shared cytokine recognition revealed in the unusually high affinity complex between IL-13 and IL-13Rα2. Lupardus PJ*, Birnbaum ME*, Garcia KC. Structure 18, 332-342 (2010). DOI: 10.1016/j.str.2010.01.003

An in vitro translation, selection, and amplification system for peptide nucleic acids. Brudno Y, Birnbaum ME, Kleiner RE, Liu DR. Nat Chem Biol. 6, 148-155 (2009). DOI: 10.1038/nchembio.280

DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes. Kleiner RE, Brudno Y, Birnbaum ME, Liu DR. J. Am. Chem. Soc. 130, 4646-4659 (2008). DOI: 10.1021/ja0753997